Targeting CGRP: Emerging Solutions in Migraine

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Release Date: December 28, 2016
Expiration Date: December 28, 2017

Expected time to complete this activity as designed: 60 minutes
There are no fees for participating in or receiving credit for this online activity.

Program Overview

In light of the evidence regarding the tremendous burden of migraine, leaders in the headache field have called for increased awareness of the availability of preventive efforts.

Dr. Diamond and Dr. Green will engage you in a lively discussion and presentation outlining the current landscape of chronic migraine including future thoughts on acute and preventative treatment. Our experts will share exciting data on new targets under development which have the potential to change the landscape of treatment in the future.

Participate in this interactive and forward-thinking activity to make sure you are prepared and “in the know” on the current and ongoing clinical trials targeting calcitonin gene-related peptide (CGRP) and their impact on the current unmet need in the treatment options for preventive treatment in migraine.

Target Audience

This activity is intended for physicians, pharmacists, and nurses who are involved in the diagnosis and management of headache patients.

Learning Objectives

Upon completion of this educational activity, participants should be able to:

  • Summarize the current landscape in the management and treatment of chronic migraine
  • Identify emerging therapies targeting CGRP in the treatment of migraine
  • Demonstrate knowledge of the role of the neuropeptide CGRP as a therapeutic target in the treatment of migraine
  • Summarize the current efficacy and safety data of CGRP monoclonal antibodies from clinical trials and their relation to other treatment options for the prevention of migraine headaches


Current Landscape in Chronic Migraine - Merle L. Diamond, MD

Current Treatment Landscape and Emerging Novel Agents

The Calcitonin Gene-Related Peptide (CGRP) Developmental Landscape

CGRP Target Immunotherapy for Migraine - Mark W. Green, MD, FAAN

Expert Perspective and Audience Engagement - Merle L. Diamond, MD, and Mark W. Green, MD, FAAN

Instructions for Participation and Credit

This activity is eligible for credit through December 28, 2017. After this date, this activity will expire and no further credit will be awarded.

  1. Read the target audience, learning objectives, and faculty disclosures.
  2. You may be asked to complete a short pre-test before accessing the educational content. This must be completed in order to move forward in the activity.
  3. Complete the educational content as designed.
  4. Complete the post-test. To receive a certificate, you must receive a passing score of 70%.
  5. Complete the activity evaluation survey to provide feedback and information useful for future programming.
  6. Certificates for CME and CNE credit may be printed immediately after successfully completing the post-test and activity evaluation. Pharmacist credit will be uploaded to CPE Monitor 4 weeks following receipt of a completed, qualified form.

Faculty Biographies

Merle L. Diamond, MD
President, Managing Director
Diamond Headache Clinic
Chicago, Illinois

Dr. Merle L. Diamond is President and Managing Director of the Diamond Headache Clinic in Chicago, Illinois. She is also an Attending Physician in Internal Medicine at Saint Joseph Hospital. In addition, she serves as Clinical Assistant Professor in the Department of Medicine of Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.

Dr. Diamond graduated with high honors from the University of Michigan, Ann Arbor, Michigan, and received her medical education from Northwestern University Feinberg School of Medicine, Chicago. She completed residencies in emergency medicine/internal medicine at McGaw Medical Center of Northwestern University, Chicago, Illinois. Dr. Diamond is board certified in internal medicine, has been trained and practiced in emergency medicine, and has been elected as a fellow of the American College of Emergency Physicians. She is a recipient of the Subspecialty Certification for Headache Medicine from the United Council for Neurologic Subspecialties.

Dr. Diamond joined the staff of the Diamond Headache Clinic in 1989 after serving as an attending physician and clinical instructor at Northwestern University Hospital, Chicago, and as an attending physician at Evanston and St. Francis Hospitals, both in Evanston, Illinois. She has contributed numerous articles to the medical literature, and has lectured extensively on various headache subjects, and in particular, the treatment of headache in the Emergency Department, women and headaches, and children with headaches. Dr. Diamond is co-editor of Diamond and Dalessio’s The Practicing Physician’s Approach to Headache, 6th Edition.

Mark W. Green, MD, FAAN
Director, Headache and Pain Medicine
Professor of Neurology, Anesthesiology, and Rehabilitation Medicine
Mount Sinai School of Medicine 
New York, New York

Dr. Mark Green received his medical degree from the Albert Einstein College of Medicine. He also received his neurology training at the Albert Einstein College of Medicine where worked in the Montefiore Headache Unit and was later appointed director. He is currently the Director of Headache and Pain Medicine, and Professor of Neurology, Anesthesiology, and Rehabilitation Medicine at the Mount Sinai School of Medicine in New York City. 

Dr. Green is certified in neurology by the American Board of Psychiatry and Neurology, were he is a fellow, and in headache medicine through the United Council for Neurologic Subspecialties. He has a long-standing interest in neuropharmacology and is a panel member of the advisory board of the Food and Drug Administration’s Section on Peripheral and Central Neurological Drugs, and also a panel member of the Nervous System Devices Committee. Dr. Green serves on the board of directors of the National Headache Foundation, and is the director of Mount Sinai’s Fellowship in Headache Medicine. He was editor-in-chief the American Academy of Neurology’s recent CONTINUUM on headache, was one of the founding editors of Cephalalgia, the international headache journal, and also served as the associate editor of Headache, the journal of the American Headache Society.

Dr. Green has been active in the practice of headache and facial pain since 1978. He has lectured throughout the world on this subject and has written numerous articles on various subjects concerning headache and facial pain. 


Accreditation Statement: MediCom Worldwide, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation Statement: MediCom Worldwide, Inc. designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
MediCom Worldwide, Inc. is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This activity is acceptable for 1.0 contact hour of Continuing Education Credit. Universal Activity Number: 827-0000-16-133-H01-P. Knowledge-based CPE activity.

In order for CPE Monitor to authenticate credit, pharmacists/technicians must provide their e-Profile ID number from NABP and date of birth (in MMDD format) when registering for a CPE program. Please make sure to provide this information in your Member Profile accessed through the login/registration on the home page of this site.
Accreditation Statement: MediCom Worldwide, Inc., 101 Washington Street, Morrisville, PA 19067 is approved by the California Board of Registered Nursing, Provider Number CEP11380. MediCom designates this CNE activity for 1.0 contact hour. Program Number: 16-133-048


As an organization accredited by the Accreditation Council for Continuing Medical Education (ACCME), Accreditation Council for Pharmacy Education (ACPE) and California State Board of Registered Nursing, MediCom Worldwide, Inc. requires everyone who is in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines “relevant financial relationships” as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest. Accordingly, the following disclosures were made.

Faculty Disclosures

Dr. Merle Diamond has received honoraria related to speakers’ bureau activities from Allergan, Inc., Avanir Pharmaceuticals, Inc., Depomed, Inc., PERNIX Therapeutics, and Teva Pharmaceutical Industries Ltd.

Dr. Mark Green has disclosed no relevant financial relationships.

Planning Committee Disclosures

The individuals listed below from MediCom Worldwide, Inc. reported the following for this activity: Joan Meyer, RN, MHA, Executive Director, has no relevant financial relationships.

Peer Reviewer Disclosure

In accordance with MediCom Worldwide, Inc. policy, all content is independently peer reviewed for balance, objectivity and commercial bias. The peer reviewers have no relevant financial relationships to disclose.

Physician Payments, Sunshine Act

MediCom Worldwide, Inc. complies with the Physician Payments Sunshine Act as part of the Affordable Care Act (ACA). Accordingly, we may be required to collect information on transfer of value provided to any covered recipient under the ACA.

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If you have any questions or concerns regarding this activity, please contact MediCom Worldwide, Inc. at 1-800-408-4242 or email us at

Provided by MediCom Worldwide, Inc.
This activity is supported by an educational grant from Teva Pharmaceuticals.

©2016 MediCom Worldwide, Inc., 101 Washington St., Morrisville, PA 19067, 800-408-4242.
No portion of this material may be copied or duplicated without the expressed permission of MediCom Worldwide, Inc.

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